● Reference
Evidence-based clinical reference monographs for 61 therapeutic peptides. Mechanisms of action, dosing protocols, contraindications, and PubMed-cited research.
61
Peptides
12
Categories
60+
Conditions
600+
Citations
Epitalon
Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on Epithalamin, a natural polypeptide extract of the pineal gland.
Copper Tripeptide-1
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring tripeptide-copper complex found in human plasma, saliva, and urine.
GSH
Glutathione (GSH) is a tripeptide (Glu-Cys-Gly) and the most abundant intracellular antioxidant in the human body.
See FDA prescribing information and PubMed citations.
NAD+
NAD+ (Nicotinamide Adenine Dinucleotide) is a critical coenzyme present in every living cell, required for >500 enzymatic reactions.
See references.
Cibinetide
ARA-290 (Cibinetide) is an 11-amino acid peptide derived from the B helix of erythropoietin (EPO).
KPV tripeptide
KPV (Lys-Pro-Val) is the C-terminal tripeptide of alpha-melanocyte stimulating hormone (α-MSH).
The intestinal barrier, a critical component of the body's defense system, plays a vital role in maintaining homeostasis by preventing the translocation of harmful substances from the gut lumen into the bloodstream.
Vasoactive Intestinal Peptide
VIP (Vasoactive Intestinal Peptide) is a 28-amino acid neuropeptide that binds VPAC1 and VPAC2 receptors (Gs-coupled → adenylyl cyclase → cAMP).
AOD9604
AOD-9604 is a synthetic peptide corresponding to the C-terminal fragment (amino acids 176-191) of human growth hormone.
Mod GRF 1-29
CJC-1295 without DAC (Modified GRF 1-29) is a synthetic 29-amino acid analog of endogenous GHRH (growth hormone-releasing hormone).
CJC-1295 with DAC
CJC-1295 with DAC (Drug Affinity Complex) is the same GHRH analog as CJC-1295 no-DAC but with a DAC moiety (a reactive amine that covalently binds to albumin after injection).
FS-344
Follistatin-344 is a 344-amino acid glycoprotein that functions as a potent inhibitor of myostatin (GDF-8) and activin A — both TGF-β superfamily members that act as endogenous brakes on muscle growth.
hGH Frag 176-191
Fragment 176-191 (HGH Frag 176-191) is the C-terminal fragment of human growth hormone corresponding to amino acids 176-191.
Growth hormone releasing peptides (GHRPs) could be widely used by cheating athletes because they produce growth hormone (GH) secretion, so may generate an ergogenic effect in the body.
Pralmorelin
GHRP-2 (Growth Hormone Releasing Peptide-2, Pralmorelin) is a synthetic hexapeptide GH secretagogue that binds GHS-R1a on pituitary somatotrophs.
Growth Hormone Releasing Peptide 6
GHRP-6 (Growth Hormone Releasing Peptide-6) is the original clinically studied GHRP — a synthetic hexapeptide that binds GHS-R1a.
HEX
Hexarelin is a synthetic hexapeptide and the MOST POTENT GH-releasing peptide per-dose among all GHRPs.
Long R3 IGF-1
IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is a modified IGF-1 with an arginine substitution at position 3 and a 13-amino acid N-terminal extension.
NNC 26-0161
Ipamorelin is a synthetic pentapeptide and the most selective growth hormone releasing peptide (GHRP) discovered.
Macrilen
12.
Ibutamoren
MK-677 (Ibutamoren) is a non-peptide, orally active ghrelin mimetic that activates GHS-R1a.
PEGylated Mechano Growth Factor
PEG-MGF (PEGylated Mechano Growth Factor) is the PEGylated form of MGF, a splice variant of IGF-1 produced specifically in response to mechanical stress (exercise, injury).
Somatropin
Recombinant 191-amino acid somatropin identical to pituitary growth hormone.
GRF 1-29
Sermorelin (GHRH 1-29) is a synthetic 29-amino acid peptide corresponding to the first 29 amino acids of endogenous GHRH — the biologically active portion.
Egrifta
Tesamorelin is a synthetic 44-amino acid GHRH analog — the ONLY GHRH analog currently FDA-approved for any indication.
DDAVP
12.
Factrel
Central precocious puberty (CPP) results from premature activation of the hypothalamic-pituitary-gonadal (HPG) axis.
Zoladex
12.
Kisspeptin-54
Kisspeptin is a hypothalamic neuropeptide encoded by the KISS1 gene that serves as the master regulator of the reproductive axis.
Gonadotropin-releasing hormone (GnRH) is the master regulator of the hypothalamic-pituitary-gonadal (HPG) axis, and therefore of fertility and reproduction.
Lupron
12.
Pitocin
Oxytocin is a 9-amino acid neuropeptide produced in the hypothalamic paraventricular and supraoptic nuclei.
Trelstar
12.
Thymus extract
A fraction of polypeptides extracted from calf or porcine thymus that promotes differentiation and maturation of T-lymphocytes.
Background/Objectives: T cell dysfunction represents a fundamental barrier to effective cancer immunotherapy.
Tα1
Thymosin Alpha-1 (Tα1) is a 28-amino acid peptide naturally produced in the thymus gland.
5-Amino-1MQ
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small molecule inhibitor of NNMT (nicotinamide N-methyltransferase).
AM833
Cagrilintide is a long-acting acylated amylin analog designed for once-weekly subcutaneous injection.
Trulicity
12.
Byetta
12.
Victoza
12.
LY3437943
Retatrutide is the first triple incretin receptor agonist, simultaneously activating GLP-1R, GIPR (glucose-dependent insulinotropic polypeptide receptor), and GcgR (glucagon receptor).
Ozempic
Semaglutide is a long-acting synthetic GLP-1 receptor agonist sharing 94% sequence homology with native GLP-1.
Mounjaro
Tirzepatide is a synthetic 39-amino acid dual GLP-1/GIP receptor agonist.
MOTS-c
MOTS-c (Mitochondrial Open Reading Frame of the Twelve S rRNA type-c) is a 16-amino acid peptide encoded in the mitochondrial genome.
Elamipretide
SS-31 (Elamipretide, Bendavia, MTP-131) is a tetrapeptide (D-Arg-Dmt-Lys-Phe-NH2) that selectively targets the inner mitochondrial membrane, concentrating >1,000-fold in mitochondria due to its alternating aromatic-cationic structure.
FPF-1070
Cerebrolysin is a porcine brain-derived peptide preparation containing enzymatically processed low-molecular-weight neuropeptides and free amino acids.
N-hexanoic-Tyr-Ile-(6) aminohexanoic amide
Dihexa is a hexapeptide derived from angiotensin IV that activates the HGF (hepatocyte growth factor) / c-Met receptor pathway.
Delta Sleep Inducing Peptide
DSIP (Delta Sleep-Inducing Peptide) is a nonapeptide (9 amino acids: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) originally isolated from rabbit brain during induced sleep.
See FDA prescribing information and PubMed citations.
Selanc
Selank is a synthetic heptapeptide derived from the naturally occurring immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg) with a Pro-Gly-Pro C-terminal extension for enzymatic stability.
Semaks
Semax is a synthetic heptapeptide analog of ACTH fragment 4-7 (Met-Glu-His-Phe) with Pro-Gly-Pro C-terminal extension.
MT-II
Melanotan II (MT-2) is a synthetic cyclic heptapeptide analog of α-MSH (alpha-melanocyte stimulating hormone).
Bremelanotide
PT-141 (Bremelanotide) is a cyclic heptapeptide melanocortin receptor agonist, primarily targeting MC4R.
Body Protection Compound
BPC-157 is a 15-amino acid pentadecapeptide derived from a cytoprotective protein in human gastric juice.
Thymosin Beta-4 Fragment
TB-500 is the synthetic, injectable actin-binding fragment of Thymosin Beta-4 (Tβ4), corresponding to the 16-amino acid LKKTETQ-containing region responsible for Tβ4's biological activity.
The immunomodulatory, anti-inflammatory and regenerative properties of the human amniotic mesenchymal stromal cells (hAMSCs) secretome are acknowledged but the understanding of the specific bioactive components remains incomplete.
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